Wuhan Fine Biotech Co., Ltd.'s TTF1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The TTF1 antibody was generated using NKX2-1 as the antigen and it reacts with Homo Sapiens, and Human.
Description
NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea(BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress(CHNRD). The antibody is specific to NKX2-1